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  Fundamental MedicineTeresa Gryder, ND

COVID-19 Links 15

4/23/2020

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Updated 4/24

1/5 of New Yorkers have had the Dread Virus
https://www.nytimes.com/2020/04/23/nyregion/coronavirus-antibodies-test-ny.html

Vitamin C Reduces ICU and Ventilator Duration, Might Help Before That
​https://todayspractitioner.com/respiratory-health/is-vitamin-c-the-unsung-covid-19-hero/#.XqMVz9NKgiN

Parisian Poop Patterns Parallel COVID-19 Cases
https://www.medrxiv.org/content/10.1101/2020.04.12.20062679v1

Arguments about ReOpening Especially Interesting Given the Politics
https://www.foxnews.com/us/americans-support-extending-coronavirus-stay-at-home-orders

Virus is Expanding in Navajo Nation
https://www.knau.org/post/northern-arizona-coronavirus-cases-grow-navajo-nation-infections-continue-surge

Hemostatic Derangement?  Washing Post Reports Clots Killing Pts
https://www.washingtonpost.com/health/2020/04/22/coronavirus-blood-clots/

Antibody Testing (Serology) Strategy
https://www.centerforhealthsecurity.org/our-work/pubs_archive/pubs-pdfs/2020/200422-national-strategy-serology.pdf

Accuracy of Current Serology Testing Variable
https://www.fiercebiotech.com/medtech/covid-19-antibody-testing-a-disaster-says-roche-ceo-as-its-diagnostics-sales-rise

Vaccination Rates in Freefall
​https://www.nytimes.com/2020/04/23/health/coronavirus-measles-vaccines.html?referringSource=articleShare

Covid Patients Should NOT Discontinue ACE Inhibitors or ARB's 
https://www.ahajournals.org/doi/abs/10.1161/CIRCRESAHA.120.317134

​
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COVID-19 Antibodies: Introd to Immunology and Vaccines

3/26/2020

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Are you an immunologist? Yeah, probably not. There aren't a lot of immunologists in the world. I'm not one, though I've studied immunology under one of the best (Dr. Heather Zwickey) and I try to keep up. It's a fast moving field. Every time I hear Dr Zwickey speak she tells us about some new receptor or cytokine that they've discovered, and a bunch of new correlations between the things we already have a little info about. 

If you don't speak the language of immunology, a lot of the talk these days won't make a lot of sense. How does the body fight off a virus? How is a vaccine made? These questions have long, complicated answers. In this post I want to teach you the basic outline of the answers, even if we don't go into all the terminology and details.

One word you're going to hear a lot about is ANTIBODIES. Antibodies are, for the most part, a good thing. Antibodies are what you have if you have gotten sick and managed to fight off the infection.

But how do you get them? 
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When you first get an infection, something has invaded your body. It could be a virus or a bacteria or a cancer cell that won't stop multiplying. The first step in fighting off such an invader is to recognize it. We have immune cells who are always on patrol for invaders. The take samples of antigens from the invader's surface and deliver them to headquarters (a lymph node). At headquarters there are cells that design and manufacture antibodies that match those antigens. Antibodies are Y-shaped proteins that stick to the antigens on the invader cells and mark them for destruction.

After the invader antigens are marked, a different set of immune cells charges out and kills them. This is when you start getting better from your illness. Unfortunately the process of noticing the invader, delivering the antigen sample to HQ, designing and making the antibodies, tagging the invader cells and killing them takes about a week. It's not fast.

When your body has never fought off a certain invader before, your immune system is said to be "naive" about it. Once you have been exposed and are making antibodies, you are said to have "immunity".

This is why vaccines are so useful. A vaccine is basically a sample of antigen injected into your system to jump-start the process of recognition, delivery, and antibody-making. If you've had the vaccine for a particular kind of invader, then your body already has the antibody designed and a few of them are already made. This cuts days off of your response time to that infection. The faster you can mark the invader with antibodies and send in the troops to destroy it, the less time it has to grow in your body and make you badly sick.

When it comes to COVID-19, we had doubts about humans making good antibodies to it, because we don't seem to develop antibodies to the other coronaviruses that cause the common cold. Without developing antibodies, we don't have immunity. We can get the common cold over and over again, and it can be just as bad as it was the last time.

But the GOOD NEWS is in, and that is that people who've had COVID-19 are making antibodies to it! That means that we will be able to make a vaccine, and that the vaccine will work. This study from China, posted today (3/26/2020), says they found 206 different antibodies to COVID-19 in the immune cells of patients that survived it. Not only are there 206 antibodies detected so far, but they stick really well to the virus. Good news indeed!

The next step after testing people for the virus is to test them for the antibodies. Some of us have already had it. Wouldn't it be great to know if you've had it yet? If you knew that your immune system had already beat this virus and was ready to beat it again, you could go work in a hospital with sick people and not worry about getting sick.

It's true, we don't know how long immunity will last after exposure and antibody response, but we will learn that in the next year or two. In the meanwhile I am encouraged that research is finding good antibodies that can be used for a vaccine. Hope is on the Horizon.
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A Fever is a Good Thing (Here's Why)

10/26/2019

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Picture
This is the author using a down jacket and cat to get warm.
​

  If you’ve ever had the flu, you know how miserable it can be. Chills and sweats, body aches, coughs and sniffles—there’s nothing about it that anyone would choose to embrace. Many people get the flu vaccine every year and while that’s not the subject of this article, I will say that most of us don’t need it. Even if you get the vaccine, you might get the flu. Even if you don’t get the flu, you could easily get a cold or some other bug. When the days get short and the air gets cold and dry, more people get sick. That’s just the way it is.

In my parents’ generation the main treatment for a cold or flu was lowering the fever. Aspirin was avoided for children because it could cause Reye’s syndrome, but Tylenol was given. These days ibuprofen or naproxen are popular options for lowering a fever. But what if lowering the fever makes you sicker in the long run? What if it impairs your body’s effort to kick the bug out?

That is exactly what is happening. If you start to feel sick and get chills, the last thing you really want to do is lower the fever. It does not help you get better any faster. Instead of popping pills intended to keep yourself from getting a fever, you want to facilitate the fever. This is because fever is part of your immune system’s way of dominating infections and kicking them out. Once you realize this, you will know what to do. You might even be able to prevent yourself from getting all the way sick.

Whenever you feel strangely cold, it could be because your body has decided to turn up its internal thermostat. Chills are a sign that your body wants to be hotter. The best thing you can do is help it get as hot as it wants. Drinking hot tea, wrapping up in a blanket, curling up next to a fire are a good start. A hot bath is great. It’s hard to keep a bathtub hot for very long so boil a kettle of water and keep it on the side to pour in (carefully!!) when your water starts to cool down. If you have access to a hot tub or sauna where you won’t infect others, those are even better. Put on a warm hat or hoodie. Make a hot water bottle and put it on your midsection or your feet. Curl up with the kittie. The only warming thing you don’t really want to do is to exercise because you probably feel really tired if you have a fever and it will only make you more tired. Get warm and rest.

If your body is getting sick, it is mounting an immune response to something. You want it to do that. You want it to get the fever because that will help it get rid of the infection. Heating treatments are used for cancer too, because heat activates the immune system. There is nothing wrong with letting your body get a degree or three warmer than it usually is!

Unfortunately as we get older our bodies don’t get fevers like they used to. Kids make great fevers, so high that they can have harmless seizures from being so hot. Adults can get good fevers, high enough to kick infections, but rarely hot enough to cause seizures. Old people sometimes don’t get fevers at all, and this is a problem, because it’s hard to tell when they have an infection, and because the infections can hang around a long time. Regular heating treatments for elders are not a bad idea even when they are not sure if they’re sick. Some elders have low body temperatures to start with so if their temperature measures as “normal” (98.6F) they actually are having a fever.

Obviously you must be careful when using boiling water, heating pads or anything hot that you do not burn someone. A body temperature of 99F or more generally counts as a fever and if it gets over 101F or so your fever is getting real. This means the body is fighting something it considers dangerous. Generally we get higher fevers from bacterial infections than from viral ones, but getting our body totally warm helps us beat viruses just like it helps us beat bacteria.

The moral of the story is that fevers are good! If you get a fever, that means you are healthy enough to have a functional immune system, and it is doing its job. If you get the chills, your body is serious about beating an infection, and the best thing you can do is to get yourself toasty warm, drink liquids, and rest. Don’t eat food, that distracts the immune system, much of which lives in the intestine. Just get yourself hot and wait it out.

When your body suddenly starts sweating and you feel way too hot, the fever has broken. It’s OK to take off your hat and get out from the covers when this happens. The fever might come back again, or it might not. If it comes back again, drink hot liquids and cover up and get warm again. Usually after a few cycles of this the illness will be over. Unlike the lingering sickness that would have happened if you lowered the fever with pills and stopped your immune system from working. So be thankful for the innate intelligence of your body and enjoy the fever! It’s what nature intended.
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Simple but Feared Treatment for the FLU

1/9/2015

 
Americans are pretty much terrified to stop eating.  In this newsletter Dr Gryder discusses why fasting is a reasonable home treatment for the flu.  If you'd like to receive future email newsletters directly to your inbox, you can sign up here.

Conventional Medicine Not Always Supported by Science

10/10/2013

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Many people have this idea that naturopathic medicine is off in lala land somewhere, and that nothing about it is based on reality.  While this could be true for some practitioners, MY practice is based on what we can deduce from what we know and what we are learning.  I base my decisions on scientific findings, and not just one study, but composites of information that add to the big picture.  I advise against using unsubstantiated treatments, and against using any new pharmaceutical drug until it has been on the market at least 10 years.

Ironically, the treatments given by many conventional doctors are not based in science or even in common sense.  Sometimes a treatment idea gets broadly adopted before it has been really studied.  Once everyone thinks that is what works, they just keep doing it.  Patients demand treatments that have no evidence behind them at all.  It takes a lot of information to turn around public opinion after the people have been brainwashed by doctors.

Take chemotherapy for example.  Chemo is poison intended to kill the cancer.  In many cases chemo causes the death of a cancer-ridden patient.  Sure, there are specific cancers which respond very well to chemo, but there are many more that do not.  Doctors will sometimes give in to a patient's desire to "do anything possible" to help, even when they know that it will not help.  It is in fact easier to give people the poison they demand, than to explain to them why they won't benefit from it.

For another example, take a look at the ACIP schedule for vaccinating babies.  While I agree that vaccination is effective for preventing epidemics, there is little evidence behind the schedule.  Vaccinating a newborn for Hepatitis C is destructive, not helpful.  The schedule for vaccination is based on convenience.  Doctors stick the babies with multiple vaccines at every wellchild visit, and don't worry about possible negative effects (and lack of benefit) from that practice.  The vaccination schedule bears some research to make sure that we are building appropriate herd immunity while also not hurting anyone's baby.

I ran across this post about statins today.  Many people take statins. Statins are drugs that stop your body from making its own cholesterol.  There is no evidence to support the use of statins for preventing heart attacks, and they may actually increase the risk of heart attacks in women.  They're also linked to the formation of cataracts, crippling muscle pain, dementia, fatigue, diabetes and erectile dysfunction.  Doctors give statins when they want to lower someone's cholesterol and don't think they can get that person to change their diet and lifestyle.  The evidence says that diet and lifestyle are FAR more effective for adjusting blood lipids than statins are.

Oh and last but not least in my list of conventional medical madness is the idea that eating cholesterol makes the body's cholesterol go up.  For 20+ years the medical establishment has been teaching that if you eat too much eggs and bacon, you will have high cholesterol.  The truth is that your body MAKES cholesterol from pasta and bread.  Your body makes cholesterol because it NEEDS cholesterol.  Cholesterol is not evil.  If your cholesterol is too low, you are sick.  People get high cholesterol from being sedentary and eating too many carbs, not from having an egg breakfast and a full and active day.

Just because something is widely accepted as the state of medicine does not mean that it is the best we can do.  We can do better.  The status quo is for dead people.  Living people have the capacity to keep learning and trying new things.  I urge you to question everything that you think you know about healthcare and health. Many things that have been accepted for a long time are about to be turned on their heads.
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    Author: Teresa Gryder

    Integrative Physician and Student of Life, Medicine, and the River.

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